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platelet derived growth factor aa  (R&D Systems)


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    R&D Systems platelet derived growth factor aa
    Platelet Derived Growth Factor Aa, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 134 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/platelet+derived+growth+factor+aa/bio_rxiv__64898__2026__03__29__715075-61-11-20?v=R%26D+Systems
    Average 95 stars, based on 134 article reviews
    platelet derived growth factor aa - by Bioz Stars, 2026-07
    95/100 stars

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    Single-cell RNA sequence analysis. A Lactate content in hPASMCs under hypoxic conditions. B Lactate content in hPASMCs <t>under</t> <t>PDGF-BB</t> stimulation conditions. C Hypoxia induces global and site-specific histone lactylation in hPASMCs. D Verification of mRNA expression of LCP1 in HPH. E Verification of mRNA expression of LCP1 in PAH F . Verification of protein expression of LCP1 in HPH. G Verification of protein expression of LCP1 in PAH. H Cell proliferation assessed by EdU assay. I Apoptpsis assessed by flow cytometry. * p < 0.05 vs normoxia; ** p < 0.01 vs normoxia; # p < 0.05 vs control; ## p < 0.01 vs control
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    Single-cell RNA sequence analysis. A Lactate content in hPASMCs under hypoxic conditions. B Lactate content in hPASMCs under PDGF-BB stimulation conditions. C Hypoxia induces global and site-specific histone lactylation in hPASMCs. D Verification of mRNA expression of LCP1 in HPH. E Verification of mRNA expression of LCP1 in PAH F . Verification of protein expression of LCP1 in HPH. G Verification of protein expression of LCP1 in PAH. H Cell proliferation assessed by EdU assay. I Apoptpsis assessed by flow cytometry. * p < 0.05 vs normoxia; ** p < 0.01 vs normoxia; # p < 0.05 vs control; ## p < 0.01 vs control

    Journal: Respiratory Research

    Article Title: Comprehensive profiling of lactylation-associated genes in pulmonary hypertension through bulk and single-cell RNA sequencing integration

    doi: 10.1186/s12931-025-03446-9

    Figure Lengend Snippet: Single-cell RNA sequence analysis. A Lactate content in hPASMCs under hypoxic conditions. B Lactate content in hPASMCs under PDGF-BB stimulation conditions. C Hypoxia induces global and site-specific histone lactylation in hPASMCs. D Verification of mRNA expression of LCP1 in HPH. E Verification of mRNA expression of LCP1 in PAH F . Verification of protein expression of LCP1 in HPH. G Verification of protein expression of LCP1 in PAH. H Cell proliferation assessed by EdU assay. I Apoptpsis assessed by flow cytometry. * p < 0.05 vs normoxia; ** p < 0.01 vs normoxia; # p < 0.05 vs control; ## p < 0.01 vs control

    Article Snippet: For drug-induced PAH modeling, Platelet-Derived Growth Factor-BB (PDGF-BB) (MCE, New Jersey, USA) was administered to hPASMCs at a concentration of 20 ng/mL.

    Techniques: Sequencing, Expressing, EdU Assay, Flow Cytometry, Control